Evaluation of Advanced Platelet-Rich Fibrin Associated with Zucchelli Technique in the Treatment of Cairo Type 1 Gingival Recession: Randomized Clinical Trial

Aims: To evaluate the effectiveness of the Coronally Advanced Flap Modified by Zucchelli with A-PRF in root coverage in patients with Cairo type I gingival recession.

Study Design: Randomized Clinical Trial.

Place and Duration of Study: Sample: Department of Periodontics, between January and April 2022.

Methodology: The Consolidated Standards of Reporting Trials 2010 protocol was followed for sample selection and distribution. It was a prospective clinical study, split-mouth parallel randomized, including 54 recessions within Group MCAF+SCTG: Zucchelli Technique + SCTG; and Group 2: Zucchelli Technique + A-PRF; 6 blood samples were collected; centrifugation (1300 rpm for 14 minutes, with G force of 210); and preparation of A-PRF membranes in the Stainless Steel Kit (Intra-Luck®). For the analysis of the results, the periodontal indices of height and width of the GR, probing depth, clinical insertion level, gingival level, keratinized tissue width, keratinized gingival tissue thickness, and sensitivity level, were used in the initial period, with 90 and 180 days of follow-up. GraphPad Prism 8.0 program® was used for statistical analysis. ANOVA and TUKEY tests were performed. Kruskall-WALLIS and DUNN tests were performed to analyze the pain parameter, with significance level of 5%.

Results: Parameters probing depth and bleeding index remained without statistically significant changes in both groups. There was improvement in parameters height and width of the recession, height of the inserted gum, thickness of the gum and level of sensitivity in both groups. There was no statistically significant difference between groups.

Conclusion: There was clinical improvement in all criteria evaluated for both groups. Thus, the Coronally Advanced Flap modified by Zucchelli associated with A-PRF is as effective as the Coronally Advanced Flap modified by Zucchelli associated with SCTG.